D. Seijkens: search on Z-Library

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1

Plasmacytoid Dendritic Cells Protect Against Atherosclerosis by Tuning T-Cell Proliferation and Activity

Daissormont, I. T. M. N., Christ, A., Temmerman, L., Sampedro Millares, S., Seijkens, T., Manca, M., Rousch, M., Poggi, M., Boon, L., van der Loos, C., Daemen, M., Lutgens, E., Halvorsen, B., Aukrust,

Journal:

Circulation Research

Year:

2011

Language:

english

File:

PDF, 4.51 MB

english, 2011

2

The role of CD154 in haematopoietic development

Seijkens, Tom, Engel, David, Tjwa, Marc, Lutgens, Esther

Journal:

Thrombosis and Haemostasis

Year:

2010

Language:

english

File:

PDF, 150 KB

english, 2010

3

Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation

Suzanne A. B. M. Aarts,Tom T. P. Seijkens…

Journal:

Journal of Neuroinflammation

Year:

2017

Language:

english

File:

PDF, 3.14 MB

english, 2017

4

Exploring immune checkpoints as potential therapeutic targets in atherosclerosis

Kusters, Pascal, Lutgens, Esther, Seijkens, Tom T P

Journal:

Cardiovascular Research

Year:

2017

Language:

english

File:

PDF, 1.90 MB

english, 2017

5

Macrophage CD40-signaling drives experimental autoimmune encephalomyelitis

Aarts, Suzanne A.B.M., Seijkens, Tom T.P., Kusters, Pascal J.H., van Tiel, Claudia M., Reiche, Myrthe E., den Toom, Myrthe, Beckers, Linda, van Roomen, Cindy P.A.A., de Winther, Menno P.J., Kooij, Gij

Journal:

The Journal of Pathology

Year:

2018

Language:

english

File:

PDF, 2.28 MB

english, 2018

6

31P NMR Study of the Impact of Dietary Manipulation on Tumor Metabolism and Response to Methotrexate

P. E. Sijens, C. J. A. van Echteld, J. P. Neijt, J. Schipper, P. B. Dunki Jacobs, P. W. de Graaf, D. Seijkens

Journal:

NMR in Biomedicine

Year:

1989

Language:

english

File:

PDF, 698 KB

english, 1989

7

Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis

Seijkens, Tom T.P., van Tiel, Claudia M., Kusters, Pascal J.H., Atzler, Dorothee, Soehnlein, Oliver, Zarzycka, Barbara, Aarts, Suzanne A.B.M., Lameijer, Marnix, Gijbels, Marion J., Beckers, Linda, den

Journal:

Journal of the American College of Cardiology

Year:

2018

Language:

english

File:

PDF, 6.33 MB

english, 2018

8

P2827Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure

Bosch, L, De Haan, J J, Seijkens, T, Van Tiel, C, Brans, M, Pasterkamp, G, Lutgens, E, De Jager, S C A

Journal:

European Heart Journal

Year:

2018

Language:

english

File:

PDF, 231 KB

english, 2018

9

The CD40-CD40L Dyad as Immunotherapeutic Target in Cardiovascular Disease

Bosmans, Laura A., Bosch, Lena, Kusters, Pascal J.H., Lutgens, Esther, Seijkens, Tom T.P.

Journal:

Journal of Cardiovascular Translational Research

Year:

2020

Language:

english

File:

PDF, 432 KB

english, 2020

10

Glucocorticoid-induced tumour necrosis factor receptor family-related protein (GITR) drives atherosclerosis in mice and is associated with an unstable plaque phenotype and cerebrovascular events in humans

Shami, Annelie, Atzler, Dorothee, Bosmans, Laura A, Winkels, Holger, Meiler, Svenja, Lacy, Michael, van Tiel, Claudia, Ta Megens, Remco, Nitz, Katrin, Baardman, Jeroen, Kusters, Pascal, Seijkens, Tom,

Journal:

European Heart Journal

Year:

2020

File:

PDF, 2.34 MB

2020

11

31P NMR study of cisplatin- and doxorubicininduced changes in tumour metabolism in rats with a cisplatin-sensitive or -resistant immunocytoma

P. E. Sijens, C. J. A. van Echteld, R. H. van Rijssel, J. J. W. Lagendijk, J. P. Neijt, W. H. de Jong, A. C. E. van der Minnen, G. de Groot, D. Seijkens

Journal:

NMR in Biomedicine

Year:

1990

Language:

english

File:

PDF, 887 KB

english, 1990

12

Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile

Lutgens, E., Lievens, D., Beckers, L., Wijnands, E., Soehnlein, O., Zernecke, A., Seijkens, T., Engel, D., Cleutjens, J., Keller, A. M., Naik, S. H., Boon, L., Oufella, H. A., Mallat, Z., Ahonen, C. L

Journal:

Journal of Experimental Medicine

Year:

2010

Language:

english

File:

PDF, 8.50 MB

english, 2010

13

Ablation of CD8α+ dendritic cell mediated cross-presentation does not impact atherosclerosis in hyperlipidemic mice

Legein, Bart, Janssen, Edith M., Theelen, Thomas L., Gijbels, Marion J., Walraven, Joep, Klarquist, Jared S., Hennies, Cassandra M., Wouters, Kristiaan, Seijkens, Tom T.P., Wijnands, Erwin, Sluimer, J

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.98 MB

english, 2015

14

The therapeutic potential of targeting CD40-TRAF6 pathway in cardiovascular Diseases

Bosch, Lena, de Haan, Judith J., Seijkens, Tom T.P., van Tiel, Claudia M., Brans, Maike A.D., Pasterkamp, Gerard, Lutgens, Esther, de Jager, Saskia C.A.

Journal:

International Journal of Cardiology

Year:

2020

File:

PDF, 141 KB

2020

15

The CD40–CD40L Dyad in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

Aarts, Suzanne A. B. M., Seijkens, Tom T. P., van Dorst, Koos J. F., Dijkstra, Christine D., Kooij, Gijs, Lutgens, Esther

Journal:

Frontiers in Immunology

Year:

2017

Language:

english

File:

PDF, 721 KB

english, 2017

16

Cardiovascular oncology

Seijkens, Tom T.P., Lutgens, Esther

Journal:

Current Opinion in Lipidology

Year:

2018

File:

PDF, 352 KB

2018

17

Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice

Poels, Kikkie, van Leent, Mandy M. T., Reiche, Myrthe E., Kusters, Pascal J. H., Huveneers, Stephan, de Winther, Menno P. J., Mulder, Willem J. M., Lutgens, Esther, Seijkens, Tom T. P.

Journal:

Year:

2020

File:

PDF, 1.58 MB

2020

18

P2827Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure

Bosch, L, De Haan, J J, Seijkens, T, Van Tiel, C, Brans, M, Pasterkamp, G, Lutgens, E, De Jager, S C A

Journal:

European Heart Journal

Year:

2018

File:

PDF, 231 KB

2018

19

The immunobiology of CD154–CD40–TRAF interactions in atherosclerosis

David Engel, Tom Seijkens, Marjorie Poggi, Maryam Sanati, Larissa Thevissen, Linda Beckers, Erwin Wijnands, Dirk Lievens, Esther Lutgens

Journal:

Seminars in Immunology

Year:

2009

Language:

english

File:

PDF, 276 KB

english, 2009

20

Discovery of Small Molecule CD40–TRAF6 Inhibitors

Zarzycka, Barbara, Seijkens, Tom, Nabuurs, Sander B., Ritschel, Tina, Grommes, Jochen, Soehnlein, Oliver, Schrijver, Roy, van Tiel, Claudia M., Hackeng, Tilman M., Weber, Christian, Giehler, Fabian, K

Journal:

Journal of Chemical Information and Modeling

Year:

2015

Language:

english

File:

PDF, 3.70 MB

english, 2015

21

Targeting Hdac3 limits foam cell formation and improves atherosclerotic plaque stability

Van den Bossche, J., Hoeksema, M.A., Gijbels, M.J.J., van der Velden, S., Sijm, A., Neele, A.E., Seijkens, T., Meiler, S., Boshuizen, M.C.S., Boon, L., Mullican, S.E., Spann, N.J., Dallinga-Thie, G.M.

Journal:

Atherosclerosis

Year:

2014

Language:

english

File:

PDF, 175 KB

english, 2014

22

Constitutive CD40-signaling in Dendritic Cells limits Atherosclerosis by provoking inflammatory bowel Disease and ensuing Cholesterol Malabsorption

Kusters, Pascal, Seijkens, Tom, Bürger, Christina, Legein, Bart, Winkels, Holger, Gijbels, Marion, Barthels, Christian, Bennett, Remy, Beckers, Linda, Atzler, Dorothee, Biessen, Erik, Brocker, Thomas,

Journal:

The American Journal of Pathology

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

23

Blocking CD40-TRAF6 interactions by small-molecule inhibitor 6860766 ameliorates the complications of diet-induced obesity in mice

van den Berg, S M, Seijkens, T T P, Kusters, P J H, Zarzycka, B, Beckers, L, den Toom, M, Gijbels, M J J, Chatzigeorgiou, A, Weber, C, de Winther, M P J, Chavakis, T, Nicolaes, G A F, Lutgens, E

Journal:

International Journal of Obesity

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

24

Inclusion complex formation of anthracycline antibiotics with cyclodextrins; a proton nuclear magnetic resonance and molecular modelling study

Otto Bekers, Jantina J. Van Den Bosch Kettenes, Steven P. Van Helden, Don Seijkens, Jos H. Beijnen, Auke Bulti, Willy J. M. Underberg

Journal:

Journal of Inclusion Phenomena and Macrocyclic Chemistry

Year:

1991

Language:

english

File:

PDF, 445 KB

english, 1991

25

Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions

Hoeksema, M. A., Gijbels, M. J., Van den Bossche, J., van der Velden, S., Sijm, A., Neele, A. E., Seijkens, T., Stoger, J. L., Meiler, S., Boshuizen, M. C., Dallinga-Thie, G. M., Levels, J. H., Boon,

Journal:

EMBO Molecular Medicine

Year:

2014

Language:

english

File:

PDF, 1.51 MB

english, 2014

26

CD40-CD40L: Linking pancreatic, adipose tissue and vascular inflammation in type 2 diabetes and its complications

Seijkens, T., Kusters, P., Engel, D., Lutgens, E.

Journal:

Diabetes and Vascular Disease Research

Year:

2013

Language:

english

File:

PDF, 495 KB

english, 2013

27

Author Correction: Ablation of CD8Î±+ dendritic cell mediated cross-presentation does not impact atherosclerosis in hyperlipidemic mice

Legein, Bart, Janssen, Edith M., Theelen, Thomas L., Gijbels, Marion J., Walraven, Joep, Klarquist, Jared S., Hennies, Cassandra M., Wouters, Kristiaan, Seijkens, Tom T. P., Wijnands, Erwin, Sluimer,

Journal:

Scientific Reports

Year:

2020

File:

PDF, 648 KB

2020

28

Hematopoietic G-protein-coupled receptor kinase 2 deficiency decreases atherosclerotic lesion formation in LDL receptor-knockout mice

Otten, J. J. T., de Jager, S. C. A., Kavelaars, A., Seijkens, T., Bot, I., Wijnands, E., Beckers, L., Westra, M. M., Bot, M., Busch, M., Bermudez, B., van Berkel, T. J. C., Heijnen, C. J., Biessen, E.

Journal:

The FASEB Journal

Year:

2013

Language:

english

File:

PDF, 483 KB

english, 2013

29

Correction to: Adaptation and validation of the Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) for the Netherlands

Wapenaar, M., Twiss, J., Wagenaar, M., Seijkens, P., van den Toorn, L., Stepanous, J., Heaney, A., van den Bosch, A., Boomars, K. A.

Journal:

Netherlands Heart Journal

Year:

2018

Language:

english

File:

PDF, 117 KB

english, 2018

30

CD40L Deficiency Protects Against Aneurysm Formation

Kusters, Pascal J.H., Seijkens, Tom T.P., Beckers, Linda, Lievens, Dirk, Winkels, Holger, de Waard, Vivian, Duijvestijn, Adriaan, Lindquist Liljeqvist, Moritz, Roy, Joy, Daugherty, Alan, Newby, Andrew

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2018

Language:

english

File:

PDF, 2.74 MB

english, 2018

31

Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8+ T cell-mediated macrophage death

Seijkens, Tom T P, Poels, Kikkie, Meiler, Svenja, van Tiel, Claudia M, Kusters, Pascal J H, Reiche, Myrthe, Atzler, Dorothee, Winkels, Holger, Tjwa, Marc, Poelman, Hessel, Slütter, Bram, Kuiper, Johan

Journal:

European Heart Journal

Year:

2018

Language:

english

File:

PDF, 1.31 MB

english, 2018

32

Hyperlipidemia Induces A Hyperinflammatory Response In T-Cells

Van Tiel, C., van Os, B., Seijkens, T., Lutgens, E.

Journal:

Atherosclerosis

Year:

2019

Language:

english

File:

PDF, 52 KB

english, 2019

33

Adaptation and validation of the Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) for the Netherlands

Wapenaar, M., Twiss, J., Wagenaar, M., Seijkens, P., van den Toorn, L., Stepanous, J., Heaney, A., van den Bosch, A., Boomars, K. A.

Journal:

Netherlands Heart Journal

Year:

2016

Language:

english

File:

PDF, 321 KB

english, 2016

34

E3 Ubiquitin Ligases as Immunotherapeutic Target in Atherosclerotic Cardiovascular Disease

Poels, Kikkie, Vos, Winnie G., Lutgens, Esther, Seijkens, Tom T. P.

Journal:

Frontiers in Cardiovascular Medicine

Year:

2020

File:

PDF, 707 KB

2020

35

Inhibition of PFKFB3 Hampers the Progression of Atherosclerosis and Promotes Plaque Stability

Poels, Kikkie, Schnitzler, Johan G., Waissi, Farahnaz, Levels, Johannes H. M., Stroes, Erik S. G., Daemen, Mat J. A. P., Lutgens, Esther, Pennekamp, Anne-Marije, De Kleijn, Dominique P. V., Seijkens,

Journal:

Frontiers in Cell and Developmental Biology

Year:

2020

File:

PDF, 5.01 MB

2020

36

Hypercholesterolemia-induced priming of hematopoietic stem and progenitor cells aggravates atherosclerosis

Seijkens, T., Hoeksema, M. A., Beckers, L., Smeets, E., Meiler, S., Levels, J., Tjwa, M., de Winther, M. P. J., Lutgens, E.

Journal:

The FASEB Journal

Year:

2014

Language:

english

File:

PDF, 633 KB

english, 2014

37

Diet-induced obesity in mice diminishes hematopoietic stem and progenitor cells in the bone marrow

van den Berg, S. M., Seijkens, T. T. P., Kusters, P. J. H., Beckers, L., den Toom, M., Smeets, E., Levels, J., de Winther, M. P. J., Lutgens, E.

Journal:

The FASEB Journal

Year:

2016

Language:

english

File:

PDF, 1.42 MB

english, 2016

38

B-Cell Cd40 Protects Against Atherosclerosis In Hypercholesterolemic Mice

Reiche, M., Kusters, P., Seijkens, T., Binder, C., Lutgens, E.

Journal:

Atherosclerosis

Year:

2019

Language:

english

File:

PDF, 47 KB

english, 2019

39

Short-term regulation of hematopoiesis by lipoprotein(a) results in the production of pro-inflammatory monocytes

Schnitzler, Johan G., Poels, Kikkie, Stiekema, Lotte C.A., Yeang, Calvin, Tsimikas, Sotirios, Kroon, Jeffrey, Stroes, Erik S.G., Lutgens, Esther, Seijkens, Tom T.P.

Journal:

International Journal of Cardiology

Year:

2020

File:

PDF, 817 KB

2020

40

Caveolin-1 deficiency decreases atherosclerosis by hampering leukocyte influx into the arterial wall and generating a regulatory T-cell response

Engel, D., Beckers, L., Wijnands, E., Seijkens, T., Lievens, D., Drechsler, M., Gerdes, N., Soehnlein, O., Daemen, M. J. A. P., Stan, R. V., Biessen, E. A. L., Lutgens, E.

Journal:

The FASEB Journal

Year:

2011

Language:

english

File:

PDF, 915 KB

english, 2011

41

Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance

Chatzigeorgiou, A., Seijkens, T., Zarzycka, B., Engel, D., Poggi, M., van den Berg, S., van den Berg, S., Soehnlein, O., Winkels, H., Beckers, L., Lievens, D., Driessen, A., Kusters, P., Biessen, E.,

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 1.82 MB

english, 2014

42

In vitro31P NMR spectroscopy of the reproductive organs of the male rat: An improved preparation method

J. Der Van Grond, D. Seijkens, W. P. Th. M. Mali

Journal:

Magnetic Resonance in Medicine

Year:

1990

Language:

english

File:

PDF, 352 KB

english, 1990

43

Immune Cell Crosstalk in Obesity: A Key Role for Costimulation?

Seijkens, T., Kusters, P., Chatzigeorgiou, A., Chavakis, T., Lutgens, E.

Journal:

Year:

2014

Language:

english

File:

PDF, 843 KB

english, 2014

44

Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure

Bosch, Lena, de Haan, Judith, Seijkens, Tom, van Tiel, Claudia, Brans, Maike, Pasterkamp, Gerard, Lutgens, Esther, de Jager, Saskia

Journal:

International Journal of Cardiology

Year:

2018

Language:

english

File:

PDF, 1.42 MB

english, 2018

45

Liposomal prednisolone promotes macrophage lipotoxicity in experimental atherosclerosis

van der Valk, Fleur M., Schulte, Dominik M., Meiler, Svenja, Tang, Jun, Zheng, Kang He, Van den Bossche, Jan, Seijkens, Tom, Laudes, Matthias, de Winther, Menno, Lutgens, Esther, Alaarg, Amr, Metselaa

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2016

Language:

english

File:

PDF, 1.23 MB

english, 2016

46

Cardiovascular Oncology: Exploring The Effects Of Immune Checkpoint Inhibitors On Experimental Atherosclerosis

Poels, K., Toom, M. den, Reiche, M., Kusters, P., Beckers, L., Seijkens, T., Lutgens, E.

Journal:

Atherosclerosis

Year:

2019

Language:

english

File:

PDF, 47 KB

english, 2019

47

âNur'turing tumor T cell tolerance and exhaustion: novel function for Nuclear Receptor Nur77 in immunity

Lith, Sanne C., Os, Bram W., Seijkens, Tom T.P., Vries, Carlie J.M.

Journal:

European Journal of Immunology

Year:

2020

File:

PDF, 1.30 MB

2020

48

Platelet CD40 Exacerbates Atherosclerosis by Transcellular Activation of Endothelial Cells and Leukocytes

Gerdes, Norbert, Seijkens, Tom, Lievens, Dirk, Kuijpers, Marijke J.E., Winkels, Holger, Projahn, Delia, Hartwig, Helene, Beckers, Linda, Megens, Remco T.A., Boon, Louis, Noelle, Randolph J., Soehnlein

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2016

Language:

english

File:

PDF, 2.67 MB

english, 2016

49

Cancer patients receiving immune checkpoint inhibitor therapy are at an increased risk for atherosclerotic cardiovascular disease

Lutgens, Esther, Seijkens, Tom T.P.

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2020

File:

PDF, 175 KB

2020

50

W7 DEFICIENT CD40-TRAF6 SIGNALING IN LEUKOCYTES PREVENTS ATHEROSCLEROSIS BY SKEWING THE IMMUNE RESPONSE TOWARDS AN ANTI-INFLAMMATORY PROFILE

Lievens, D., Beckers, L., Wijnands, E., Soehnlein, O., Zernecke, A., Seijkens, T., Engel, D., Naik, S., Boon, L., Oufella, A., Mallat, Z., Noelle, R., de Winther, M., Daemen, M., Biessen, E., Weber, C

Journal:

Atherosclerosis Supplements

Year:

2010

Language:

english

File:

PDF, 61 KB

english, 2010

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